The Existence of original drug molecules in ultra high dilutions


  • Dr Sanjib Chattopadhyay Principal of a college



Atomic absorption spectrophotometry, homeopathy, nanoparticle, Serial dilution, UV-Vis spectroscopy.




Background: Some workers postulated that homeopathic medicines have got some alterations of hydrogen bonded network in water molecules for their activity, but according to others the original drug molecule remains present as nanoparticles. Objective: To prove experimentally whether traces of medicine molecules are present in ultra high dilution and determine its apparent cause. Materials and Methods: To detect existence of Copper ion in 5 ultra high dilutions (6c, 30c, 200c, 1000c and 10000c) in Cuprum metallicum were subjected to Atomic Absorption Spectrophotometry. An experiment was also set up to determine how one can obtain trails of original molecules in highly diluted solutions beyond Avogadro’s limit where a solution of copper sulfate was successively diluted decimally in three different ways: NSW (Non-”Succussed” Water), SW(“Succussed” Water), SWE (“Succussed” Water with 50% ethanol) and was studied by UV-Vis Spectrophotometer. Result: Existence of a Copper ion was found asymptotically decreasing through all the five dilutions. In the second experiment it was observed that in case of NSW solution the Optical Density (OD) reaches to non-detectable (ND) range earlier, but for SW and SWE later. Conclusion: Some sorts of non-homogeneity established in “succussed” alcoholic dilutions due to fall of dielectric constant. With the increase of dilution more proportion of solute molecules in the form of nanoparticles covered by solvent layers become transferred to the next serial dilution. Drugs, tightly packed by ethanol (‘nanoparticles’) easily enter inside cell, bring symptoms to the “provers” and cure patients as well when applied in minute dose.

Author Biography

Dr Sanjib Chattopadhyay, Principal of a college

Dr Sanjib Chattopadhyay is the Principal of Bangabasi Evening College, Affiliated to University of Calcutta, Kolkata 700009, Professor, Dept. Of Zoology, formerly he served as Associate Professor, Dept of Zoology, B.K.C. College Kolkata 700108, India under West Bengal State University.




How to Cite

Chattopadhyay, D. S. (2023). The Existence of original drug molecules in ultra high dilutions. International Journal of High Dilution Research - ISSN 1982-6206, 22(2), 41–41.