International Journal of High Dilution Research - ISSN 1982-6206 https://highdilution.org/index.php/ijhdr <div style="width: 100%; text-align: justify; font-size: 12px;">IJHDR is a full submission free / open-access electronic journal specialized in the multidisciplinary field of High Dilution (HD) research. Hosted by GIRI (https://giri-society.org/) and supported by HRI (https://www.hri-research.org/), HD Science (https://www.hdscience.com.br/), and ECH (https://homeopathyeurope.org/), IJHDR works in a double-blinded peer-reviewed system, counting on an international editorial board. From June 2022, the annual periodicity was set to a continuous flow system.</div> <div style="width: 100%; text-align: justify; font-size: 12px;">The journal is indexed at LILACS/BIREME/PAHO/WHO and EBSCO and inserted at SCOPUS, Qualis-CAPES, Latindex, OJS/PKP, Google Scholar, DOAJ, NSDL/NSF, Open J-Gate, JournalSeek, Scimago, and BVS. The H index is 9 (2021).</div> <div style="width: 100%; text-align: justify; font-size: 12px;">IJHDR counts on the services of ABEC and Crossref. Eventual plagiarism is checked by the iThenticate service.</div> <div style="width: 100%; text-align: justify; font-size: 12px;">IJHDR adopts the ethical standards described by the Committee on Publication Ethics (COPE) and the International Committee of Medical Journal Editors (ICMJE). </div> <div style="width: 100%; text-align: justify; font-size: 12px;">The average time between submission and publication is 6 - 8 months.</div> <div style="width: 100%; text-align: justify; font-size: 12px;"> <p>Since August 2021, IJHDR adopts the Creative-Commons license: <strong><span class="cc-license-title">Attribution-NonCommercial-ShareAlike 4.0 International</span> <span class="cc-license-identifier">(CC BY-NC-SA 4.0).</span></strong></p> </div> Groupe International de Recherche sur l'Infinitesimal - GIRI en-US International Journal of High Dilution Research - ISSN 1982-6206 1982-6206 <p>&lt;a rel="license" href="http://creativecommons.org/licenses/by-nc-sa/4.0/"&gt;&lt;img alt="Creative Commons License" style="border-width:0" src="https://i.creativecommons.org/l/by-nc-sa/4.0/88x31.png" /&gt;&lt;/a&gt;&lt;br /&gt;This work is licensed under a &lt;a rel="license" href="http://creativecommons.org/licenses/by-nc-sa/4.0/"&gt;Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License&lt;/a&gt;.</p> Advance Teaching of Fundamentals of Homoeopathy (ATFH): Redefining Competency Based Approach. https://highdilution.org/index.php/ijhdr/article/view/1141 Aditya Dilipkumar Patil Copyright (c) 2022 Aditya Dilipkumar Patil https://creativecommons.org/licenses/by-nc-sa/4.0 2022-06-19 2022-06-19 21 cf 1 3 10.51910/ijhdr.v21icf.1141 Observations on 73 Vaccine breakthrough COVID-19 infected patients and its individualized homeopathic treatment https://highdilution.org/index.php/ijhdr/article/view/1127 <p>Background: Since the initiation of vaccine rollout, breakthrough COVID-19 infections have been reported. While conventional therapy is the accepted mode of treatment, there has been little recognition of the role played by the alternative therapies like homeopathy. The purposes of this study were to identify the clinico-symptomatic profile of the vaccine breakthrough covid-19 infections and to assess the response of individualized homoeopathic treatment in these breakthrough cases.</p> <p>Methods: A retrospective data analysis of patients treated with homoeopathic medicines who confirmed the breakthrough infection criteria: positive infection ≥14 days after completion of both the recommended doses of an authorized COVID-19 vaccine was conducted. IBM SPSS Statistics 21.0 was used for data analysis with a p-value below 0.05 defined as significant. WHO Clinical Progression Scale and Outcome in Relation to Impact on Daily Living score were used as outcome measures.</p> <p>Results: In total 73 cases were reported to be vaccine breakthrough infections. The median recovery time reported in the data set was 9 ± 2 days. While 5 patients dropped out, 68 (93.15%) patients responded positively to homeopathic treatment, and 55 (75.34%) recovered completely with normalized serological markers/ nasal swabs/ HRCT Chest. About 29 (39.72%) of these presented with mild clinical manifestations, 26 (35.61%) moderate, 17 (23.28%) severe and 1 (1.36%) was critical. 10 homeopathic remedies were prescribed to these 73 patients. Majority of the patients attained an ORIDL score of 4. Maximum patients reported a WHO clinical Progression score of 3. Statistical analysis showed a significant response to homeopathic treatment in the study group.</p> <p>Conclusion: Vaccine breakthrough cases occur in a fraction of vaccinated people. Despite the limited number of study subjects, homoeopathy showed some promising results in the present setup. The response rate was highest in the moderate and severe cases which suggest the importance of consideration of alternative medicine in the current pandemic. Further exploratory research studies and comparative clinical trials may be encouraged.</p> Gyandas Wadhwani Aditi Chadha Copyright (c) 2022 Gyandas Wadhwani, Aditi Chadha https://creativecommons.org/licenses/by-nc-sa/4.0 2022-07-03 2022-07-03 21 cf 04 17 10.51910/ijhdr.v21icf.1127 A case report of Budd-Chiari syndrome with cardiac complications and low SpO2 successfully managed by an Integrated-approach https://highdilution.org/index.php/ijhdr/article/view/1120 <p>Budd-Chiari syndrome [BCS] is a rare, potentially life-threatening condition characterized by the triad of abdominal pain, ascites, and hepatomegaly (with or without jaundice). There will be an underlying disorder in most cases. The diagnosis, as well as management of the case, requires a multidisciplinary approach. The treatment should aim at reducing the presenting symptoms as well as removing the underlying pathology. Here we explain a case report of a 21-year-old male patient in the subacute stage of BCS with its complications and considered as a candidate for liver transplantation. His liver enzymes, PT/INR, D- dimer, and homocysteine values were above normal levels. The arterial oxygen saturation level was subnormal, and he was on supportive oxygen supplement. Inferior venacava [IVC] Doppler revealed a non-obstructive intrahepatic thrombus. The patient was treated with Homoeopathic medicine <em>Arsenicum album</em> and <em>Arnica montana</em>, given as an adjuvant to conventional treatment.</p> E.R. Vinitha Abraham Elizabeth K Sudheer RN Sharma B Preetha Copyright (c) 2022 E.R. Vinitha https://creativecommons.org/licenses/by-nc-sa/4.0 2022-07-25 2022-07-25 21 cf 27 45 10.51910/ijhdr.v21icf.1120 Optimization of Homoeopathy in the management of Post-Traumatic Stress Disorder, the aftermath of COVID-19 pandemic: Clinical Case Series https://highdilution.org/index.php/ijhdr/article/view/1140 <p><strong>Background &amp; Objectives: </strong>Psychological fragility caused to human life has been the largest aftermath of the pandemic posing a raised public health concern globally. This psychological impact is identified as Post-Traumatic Stress Disorder (PTSD) which was the most commonly diagnosed psychological disorder during this pandemic. These cases, if left untreated and unidentified may take a devastating transformation into psychotic disorders and cause gross damage to the individual and the community by disrupting human relations. Keeping in view the beneficial role of Homoeopathy in dealing with psychological disorders based on its philosophy and previous studies, a clinical case series of 10 PTSD cases successfully treated with Homoeopathy during this pandemic are presented here.</p> <p><strong>Method:</strong> 10 cases of PTSD consulted during the first wave of pandemic diagnosed based on the clinical picture analogous to PTSD cluster symptomatology from Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) and objectively through Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) were treated with Homoeopathic intervention. Homeopathic medicine was prescribed based on the totality of each case through repertorization and in consultation with the sourcebooks of Homoeopathic Materia Medica (HMM). The cases were followed monthly for clinical improvement and every three months using the CAPS-5 score. The outcome was assessed after six months clinically and objectively through the CAPS-5 score. At the end of one year, further to assess the casual attribution of clinical outcome to homoeopathic intervention, validated MONARCH (Modified Naranjo Criteria for Homoeopathy) tool was utilized.</p> <p><strong>Results: </strong>The 10 diagnosed PTSD cases showed marked improvement assessed after one year of Homoeopathic treatment. Significant improvement was found in the clinical picture affirmed through CAPS-5 score and MONARCH tool.</p> <p><strong>Conclusion: </strong>Homoeopathic medicines showed a significantly beneficial role in the management of PTSD during the pandemic in the presented 10 cases. Further validation through well-designed clinical trials is warranted.</p> Hima Bindu Ponnam Copyright (c) 2022 Hima Bindu Ponnam https://creativecommons.org/licenses/by-nc-sa/4.0 2022-08-12 2022-08-12 21 cf 46 66 10.51910/ijhdr.v21icf.1140 Investigation of the Influence of clathrate hydrate crystals on the Structuring of Homeopathic High Dilutions https://highdilution.org/index.php/ijhdr/article/view/1153 <p>High dilutions (HD) of drugs used in homeopathy are mostly too dilute to contain original drug molecules. But evidences support their specific biological and therapeutic effects. The reason behind this is thought to be water structure characteristic of the original drug.&nbsp; Spectroscopic studies indicate that the specific water structure in HDs can be resolved into free water molecules, hydrogen bonding strength of water hydroxyl, number of hydrogen bonds and clathrate hydrate crystals (CHC). HDs are prepared in EtOH water solution by serial dilution and mechanical agitation, and are called potencies. The objective of the present study is to further confirm the presence of CHCs in the two potencies of three drugs. Electronic spectra of the HDs of the potencies indicate two broad peaks and marked difference in intensities of absorption. Furior Transform Infrared (FT-IR) spectra of the test potencies and their control show difference in intensity shift and contour shape of OH stretching and bending bands. All the experimental data indicate the presence of CHCs in varying amounts in the test potencies.</p> Nirmal Sukul Sumit Ghosh Raj Kumar Singh Nivedita Pande Anirban Sukul Copyright (c) 2022 Nirmal Sukul, Sumit Ghosh, Raj Kumar Singh, Nivedita Pande, Anirban Sukul https://creativecommons.org/licenses/by-nc-sa/4.0 2022-07-03 2022-07-03 21 cf 18 26 10.51910/ijhdr.v21icf.1153